PARAGARD T 380A

LOE Approaching

copper

NDAINTRAUTERINESYSTEM
Approved
Nov 1984
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
12

Mechanism of Action

Paragard. Mechanism(s) by which copper enhances contraceptive efficacy include interference with sperm transport and fertilization of an egg, and possibly prevention of implantation.

Pharmacologic Class:

Copper-containing Intrauterine Device

Clinical Trials (5)

NCT04422431Phase 2Completed

Copper Concentration & Histopathologic Changes in Liver Biopsy in Participants With Wilson Disease Treated With ALXN1840

Started Dec 2020
31 enrolled
Wilson Disease
NCT04573309Phase 2Completed

Copper and Molybdenum Balance in Participants With Wilson Disease Treated With ALXN1840

Started Sep 2020
9 enrolled
Wilson Disease
NCT04594252Phase 1Completed

Copper Balance in Healthy Participants Administered ALXN1840

Started Jul 2020
17 enrolled
Healthy
NCT02957292Phase 4Completed

A Study to Compare the Menstrual Bleeding Profile Among Jaydess® and Copper Intrauterine Device (IUD) Users. COLIBRI STUDY (Copper and Levonorgestrel IUD Barcelona Research Initiative).

Started Jun 2016
108 enrolled
Contraception
NCT02763215N/ACompleted

The Assessment of Copper Parameters in Wilson Disease Participants on Standard of Care Treatment

Started May 2016
64 enrolled
Wilson Disease