PAPA-DEINE #4 (acetaminophen; codeine phosphate) by Johnson & Johnson is clinical pharmacology mechanism of action codeine is an opioid agonist relatively selective for the mu-opioid receptor, but with a much weaker affinity than morphine. Approved for mild to moderate pain, where treatment with an opioid is appropriate, for which alternative treatments are inadequate. First approved in 1984.
Drug data last refreshed 18h ago
CLINICAL PHARMACOLOGY Mechanism of Action Codeine is an opioid agonist relatively selective for the mu-opioid receptor, but with a much weaker affinity than morphine. The analgesic properties of codeine have been speculated to come from its conversion to morphine, although the exact mechanism of…
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