PACLITAXEL by Hikma is depolymerization. Approved for breast cancer after failure of combination chemotherapy for metastatic disease, relapse within 6 months of adjuvant chemotherapy. First approved in 2002.
Drug data last refreshed 18h ago
depolymerization. This stability results in the inhibition of the normal dynamic reorganization of the microtubule network that is essential for vital interphase and mitotic cellular functions. Paclitaxel induces abnormal arrays or "bundles" of microtubules throughout the cell cycle and multiple…
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