OXYBUTYNIN CHLORIDE

Post-LOE

oxybutynin chloride

ANDAORALTABLET
Approved
Apr 2020
Lifecycle
Post-LOE
Competitive Pressure
30/100
Clinical Trials
3

Mechanism of Action

CLINICAL PHARMACOLOGY Oxybutynin chloride exerts a direct antispasmodic effect on smooth muscle and inhibits the muscarinic action of acetylcholine on smooth muscle. Oxybutynin chloride exhibits only one fifth of the anticholinergic activity of atropine on the rabbit detrusor muscle, but four to…

Clinical Trials (3)

NCT02961790Phase 3Completed

Oxybutynin Chloride in Managing Hot Flashes

Started Dec 2016
150 enrolled
Breast CarcinomaDuctal Breast Carcinoma In SituHot Flashes+2 more
NCT00613327Phase 4Completed

An Efficacy and Safety Study of Oxybutynin Chloride Oral Osmotic Therapeutic System (OROS) in Korean Overactive Bladder Participants

Started Sep 2007
345 enrolled
Urinary Bladder, Overactive
NCT00990886Phase 2Completed

The Effect of Extended-Release Oxybutynin Chloride on Vasomotor Symptoms in Healthy Post-Menopausal Women

Started Apr 2004
148 enrolled
MenopauseHot Flashes