OSENI

Peak

alogliptin benzoate and pioglitazone hydrochloride

NDAORALTABLET
Approved
Jan 2013
Lifecycle
Peak
Competitive Pressure
8/100
Clinical Trials
25

Mechanism of Action

agents: alogliptin and pioglitazone. Alogliptin Increased concentrations of the incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are released into the bloodstream from the small intestine in response to meals. These hormones cause…

Clinical Trials (5)

NCT03042325Phase 4Withdrawn

Safety and Efficacy of Alogliptin in Indian Participants With Type 2 Diabetes Mellitus

Started Jul 2017
0
Diabetes Mellitus, Type 2
NCT03555565N/ACompleted

Specified Drug-Use Survey of Alogliptin and Metformin Hydrochloride Combination Tablets "Survey on Long-term Use in Type 2 Diabetes Mellitus Patients With Renal or Hepatic Impairment or Advanced Age"

Started Feb 2017
1,026 enrolled
Type 2 Diabetes Mellitus
NCT02856113Phase 3Completed

Phase 3 Alogliptin Pediatric Study

Started Oct 2016
152 enrolled
Diabetes Mellitus, Type 2
NCT02756832N/ACompleted

An Observational Study of Alogliptin Benzoate in Participants With Diabetes Mellitus Type 2

Started Sep 2016
1,409 enrolled
Diabetes Mellitus
NCT02508168Phase 1Completed

Phase 1 Bioavailability Study of SYR-322MET

Started Apr 2016
24 enrolled
Healthy Volunteers

Loss of Exclusivity

LOE Date
Jun 4, 2029
39 months away
Patent Expiry
Jun 4, 2029

Patent Records (2)

Patent #ExpiryTypeUse Code
7807689
Jun 27, 2028
SubstanceProduct
U-1337
8637079
Jun 4, 2029
Product