ORAVERSE

LOE Approaching

phentolamine mesylate

NDAINJECTIONINJECTABLE
Approved
May 2008
Lifecycle
LOE Approaching
Competitive Pressure
30/100

Mechanism of Action

soft-tissue anesthesia and the associated functional deficits is not fully understood. Phentolamine mesylate, the active ingredient in OraVerse, produces an alpha-adrenergic block of relatively short duration resulting in vasodilatation when applied to vascular smooth muscle. In an animal model,…