ONTRALFY

Growth

tizanidine hydrochloride

NDAORALSOLUTION
Approved
Dec 2024
Lifecycle
Growth
Competitive Pressure
0/100

Mechanism of Action

alpha-2-adrenergic receptor agonist and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. The effects of tizanidine are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons.

Indications (1)

Loss of Exclusivity

LOE Date
May 7, 2042
196 months away
Patent Expiry
May 7, 2042

Patent Records (2)

Patent #ExpiryTypeUse Code
12042484
May 7, 2042
Product
U-2779
12263158
May 7, 2042
Product
U-2779