NDAORALSUSPENSION
Approved
Dec 2012
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
4/8 — Partial
ONFI (clobazam) by Lundbeck is cytochrome p450 2d6 inhibitors [moa]. First approved in 2012.
Drug data last refreshed 2h ago · AI intelligence enriched 3d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ONFI (clobazam) is an oral benzodiazepine suspension approved in 2012 as an adjunctive antiepileptic agent. It works primarily through cytochrome P450 2D6 inhibition to reduce seizure frequency. The drug is indicated for seizure management in patients with epilepsy, particularly those requiring add-on therapy.
$32MPart D
PeakStable
Product is at peak commercial maturity with modest Part D penetration (~10K claims annually); team likely focused on market maintenance rather than expansion.
Mechanism of Action
Cytochrome P450 2D6 Inhibitors
Pharmacologic Class:
Benzodiazepine
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
The Variation in Electrode Configuration for Termination of Out-of-Hospital Rhythms That Are Shockable in Cardiac Arrest Trial
Started Apr 2027
1,500 enrolled
Cardiac Arrest (CA)
A Study to Confirm Efficacy of a Single Dose of Baloxavir Marboxil in the Post-exposure Prophylaxis (PEP) of Influenza Virus Infection in Chinese Participants
Started Sep 2026
325 enrolled
Influenza, HumanRespiratory Tract InfectionsPost-exposure Prophylaxis
Single-arm, Multi-center Study Evaluating the Acceptance and Feasibility of a Digital Remote Monitoring Tool Configured for Patients With ATTR-CM: ACO-Monitor
Started Aug 2026
60 enrolled
Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Evaluation of a Vaccine Chatbot on HPV Vaccine Confidence and Hesitancy
Started Aug 2026
1,800 enrolled
HPV Vaccine
Confirmatory Study of Govorestat in CMT-SORD
Started May 2026
0Charcot-Marie-Tooth Disease With Sorbitol Dehydrogenase Deficiency (CMT-SORD)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.