NDAORALTABLET
Approved
Oct 2011
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
3/8 — Basic
ONFI (clobazam) by Lundbeck is cytochrome p450 2d6 inhibitors [moa]. First approved in 2011.
Drug data last refreshed 9h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ONFI (clobazam) is an oral benzodiazepine approved in 2011 that acts as a cytochrome P450 2D6 inhibitor. It is indicated for seizure management in epilepsy patients. The drug works by enhancing GABAergic inhibition in the central nervous system.
Peak
Peak lifecycle status indicates established market position with stable revenue generation; brand team likely operating at steady-state scale focused on market maintenance.
Mechanism of Action
Cytochrome P450 2D6 Inhibitors
Pharmacologic Class:
Benzodiazepine
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
Single-arm, Multi-center Study Evaluating the Acceptance and Feasibility of a Digital Remote Monitoring Tool Configured for Patients With ATTR-CM: ACO-Monitor
Started Aug 2026
60 enrolled
Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Evaluation of a Vaccine Chatbot on HPV Vaccine Confidence and Hesitancy
Started Aug 2026
1,800 enrolled
HPV Vaccine
Confirmatory Study of Govorestat in CMT-SORD
Started May 2026
0Charcot-Marie-Tooth Disease With Sorbitol Dehydrogenase Deficiency (CMT-SORD)
A Study in Pediatric Participants Aged ≥2 to <12 Years With a Suspected or Confirmed Bacterial Infection or Receiving Prophylaxis Antibiotics
Started Apr 2026
20 enrolled
Urinary Tract Infections
Confirmatory Clinical Study in Active Ulcerative Colitis
Started Apr 2026
204 enrolled
Colitis, Ulcerative
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.