OLMESARTAN MEDOXOMIL, AMLODIPINE AND HYDROCHLOROTHIAZIDE
Post-LOEolmesartan medoxomil and amlodipine besylate and hydrochlorothiazide
ANDAORALTABLET
Approved
May 2025
Lifecycle
Post-LOE
Competitive Pressure
30/100
Clinical Trials
1
Mechanism of Action
medoxomil, amlodipine, and hydrochlorothiazide tablets target three separate mechanisms involved in blood pressure regulation. Specifically, amlodipine blocks the contractile effects of calcium on cardiac and vascular smooth muscle cells; olmesartan medoxomil blocks the vasoconstriction and sodium…
Pharmacologic Class:
Thiazide Diuretic
Clinical Trials (1)
Efficacy and Safety Study of Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide Combination Therapy in Patients With Hypertension Not Controlled With Olmesartan Medoxomil and Hydrochlorothiazide Combination Therapy
Started Apr 2013
344 enrolled
Essential Hypertension