OFLOXACIN

Post-LOE

ofloxacin

ANDAOPHTHALMICSOLUTION/DROPS
Approved
Apr 2008
Lifecycle
Post-LOE
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

CLINICAL PHARMACOLOGY Pharmacokinetics: Serum, urine and tear concentrations of ofloxacin were measured in 30 healthy women at various time points during a ten-day course of treatment with ofloxacin ophthalmic solution. The mean serum ofloxacin concentration ranged from 0.4 ng/mL to 1.9 ng/mL.…

Pharmacologic Class:

Quinolone Antimicrobial

Clinical Trials (5)

NCT06815536N/ARecruiting

Master Protocol for Evaluating Multiple Infection Diagnostics for Ciprofloxacin-Resistant Neisseria Gonorrhoeae

Started Apr 2025
3,291 enrolled
Neisseria Gonorrheae Infection
NCT04678869N/AActive Not Recruiting

CiproPAL (Ciprofloxacin Prophylaxis in Acute Leukaemia)

Started Jun 2022
313 enrolled
Acute Lymphoblastic Leukaemia - Category
NCT03828201Phase 2Recruiting

Efficacy and Tolerability of Bedaquiline, Delamanid, Levofloxacin, Linezolid, and Clofazimine to Treat MDR-TB

Started Jun 2022
220 enrolled
Tuberculosis, Multidrug-Resistant
NCT04636957Phase 3Unknown

A Phase III Study of Ciprofloxacin Plus Fluocinolone in Acute Otitis Externa (AOE)

Started Nov 2020
600 enrolled
Acute Otitis Externa
NCT04147260Phase 1Completed

Evaluation of Photosafety of BI 730357 Compared to Placebo and the Known Photosensitizing Agent Ciprofloxacin

Started Nov 2019
85 enrolled
Healthy