NDAOPHTHALMICSOLUTION/DROPS1 Generic Approved
Approved
Jul 1993
Lifecycle
LOE Approaching
Competitive Pressure
45/100
Clinical Trials
20
Data completeness
4/8 — Partial
OCUFLOX (ofloxacin) by AbbVie. Approved for quinolone antimicrobial [epc]. First approved in 1993.
Drug data last refreshed 3h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
OCUFLOX (ofloxacin) is a quinolone antimicrobial ophthalmic solution approved in 1993 for bacterial eye infections. It works by inhibiting bacterial DNA gyrase, preventing DNA replication in susceptible organisms. The drug is administered as eye drops directly to the affected eye.
$0.006BPart D
LOE ApproachingDeclining
Declining Part D utilization and nearing loss of exclusivity signals a contracting team focused on legacy product management and generic transition planning.
Mechanism of Action
Pharmacologic Class:
Quinolone Antimicrobial
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
Master Protocol for Evaluating Multiple Infection Diagnostics for Ciprofloxacin-Resistant Neisseria Gonorrhoeae
Started Apr 2025
2,627 enrolled
Neisseria Gonorrheae Infection
A Study of Levofloxacin Ocular Implant in Patients Undergoing Routine Bilateral Cataract Surgery
Started Jun 2023
0Cataract
A Phase 1, Open-Label Study to Evaluate the Effect of a Low-Fat Meal and Multiple Doses of Ciprofloxacin on the Pharmacokinetics of Vorasidenib in Healthy Subjects
Started Apr 2023
64 enrolled
Healthy Subjects
CiproPAL (Ciprofloxacin Prophylaxis in Acute Leukaemia)
Started Jun 2022
313 enrolled
Acute Lymphoblastic Leukaemia - Category
Efficacy and Tolerability of Bedaquiline, Delamanid, Levofloxacin, Linezolid, and Clofazimine to Treat MDR-TB
Started Jun 2022
271 enrolled
Tuberculosis, Multidrug-Resistant
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.