NDAINJECTIONINJECTABLEPriority Review
Approved
Jun 1994
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
Priority Review
OCTREOSCAN (indium in -111 pentetreotide) by Curium Pharma is clinical pharmacology general pentetreotide is a dtpa conjugate of octreotide, which is a long-acting analog of the human hormone, somatostatin. First approved in 1994.
Drug data last refreshed 7h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
OCTREOSCAN (Indium In-111 Pentetreotide) is a diagnostic imaging agent that binds to somatostatin receptors on neuroendocrine tumors and receptor-rich normal tissues. It is a radiolabeled octreotide analog conjugated to DTPA that concentrates in tumors within one hour of injection, enabling visualization after background clearance. The agent is used to localize somatostatin receptor-expressing neuroendocrine tumors for diagnostic and staging purposes.
LOE Approaching
Product is in late-stage lifecycle with approaching loss of exclusivity, indicating team focus on transition strategy and retention against generic/biosimilar competition.
Mechanism of Action
CLINICAL PHARMACOLOGY General Pentetreotide is a DTPA conjugate of octreotide, which is a long-acting analog of the human hormone, somatostatin. Indium In 111 pentetreotide binds to somatostatin receptors on cell surfaces throughout the body. Within an hour of injection, most of the dose of indium…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.