OCTREOSCAN

LOE ApproachingPeptide

indium in -111 pentetreotide

NDAINJECTIONINJECTABLEPriority Review
Approved
Jun 1994
Lifecycle
LOE Approaching
Competitive Pressure
30/100

Mechanism of Action

CLINICAL PHARMACOLOGY General Pentetreotide is a DTPA conjugate of octreotide, which is a long-acting analog of the human hormone, somatostatin. Indium In 111 pentetreotide binds to somatostatin receptors on cell surfaces throughout the body. Within an hour of injection, most of the dose of indium…