NUMBRINO
Peakcocaine hydrochloride nasal
NDANASALSOLUTION
Approved
Jan 2020
Lifecycle
Peak
Competitive Pressure
0/100
Data completeness
3/8 — Basic
NUMBRINO (cocaine hydrochloride nasal) is type. First approved in 2020.
Drug data last refreshed 5d ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
NUMBRINO is a nasal solution formulation of cocaine hydrochloride approved in 2020 for topical use. It works by reversibly blocking voltage-gated sodium channels in nerve fibers, preventing action potential generation and providing local anesthesia and vasoconstriction. This is a niche specialty pharmaceutical with established clinical utility in specific medical procedures.
Peak10.8 years to LOE
NUMBRINO is in peak commercial phase with strong patent protection through 2037, supporting a stable but specialized commercial team focused on procedure-based utilization.
Mechanism of Action
type. Cocaine hydrochloride prevents conduction in nerve fibers by reversibly blocking voltage-gated sodium channels and preventing the transient rise in sodium conductance necessary for generation of an action potential.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on NUMBRINO offers career stability in a niche, highly specialized segment with extended patent protection and limited competitive pressure. This role emphasizes deep procedure-based medical knowledge, healthcare system relationships, and regulatory expertise rather than broad market development.
Specialty Brand Manager
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.