BLAINJECTIONINJECTABLE2 Generics Approved
Approved
Jul 1991
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
4/8 — Partial
NOVOLIN N (human insulin) by Novo Nordisk. Approved for insulin [epc]. First approved in 1991.
Drug data last refreshed 1h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
NOVOLIN N is a human insulin (NPH) injectable formulation approved in 1991 for the treatment of diabetes mellitus. It is a basal insulin that provides intermediate-acting glycemic control, typically used in combination with rapid-acting insulins or oral agents. The drug works by facilitating glucose uptake in peripheral tissues and suppressing hepatic glucose production.
$0.053BPart D
LOE ApproachingDeclining
Product approaching loss of exclusivity with $53M in annual Part D spending; brand teams are shifting to defensive positioning and cost optimization strategies.
Mechanism of Action
Pharmacologic Class:
Insulin
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
Defining the Human Insulin Resistance Molecular Network; SIGNATURE
Started Jan 2026
80 enrolled
Metabolic HealthInsulin Sensitivity/Resistance
A Trial to Investigate Post Prandial Blood Glucose Control With Fast-acting Human Insulin HinsBet® Compared to Insulin Lispro (Humalog®) and Regular Human Insulin (Huminsulin® Normal) After Ingestion of a Standardized Meal in Subjects With T1DM
Started Apr 2016
36 enrolled
Type 1 Diabetes Mellitus
A Double-blinded, Randomised, Three-period Crossover Euglycaemic Clamp Trial Investigating the Pharmacokinetics, Glucodynamics and Safety of BioChaperone Human Insulin, Human Insulin (Huminsulin® Normal) and Insulin Lispro (Humalog®) in Subjects With Type 1 Diabetes
Started Aug 2014
38 enrolled
Diabetes Mellitus Type 1
A Study of LY2605541 (Insulin Peglispro) and Human Insulin Concentrations in Fat Tissue
Started Apr 2014
24 enrolled
Diabetes Mellitus, Type 1
Investigating Efficacy and Safety of Biphasic Insulin Aspart 50 Twice Daily Versus Biphasic Human Insulin 50 Twice Daily Both in Combination With Metformin in Chinese Subjects With Type 2 Diabetes Mellitus
Started Jun 2013
161 enrolled
DiabetesDiabetes Mellitus, Type 2
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.