NORPRAMIN

LOE Approaching

desipramine hydrochloride

NDAORALTABLET
Approved
Nov 1964
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
4

Mechanism of Action

Mechanism of Action Available evidence suggests that many depressions have a biochemical basis in the form of a relative deficiency of neurotransmitters such as norepinephrine and serotonin. Norepinephrine deficiency may be associated with relatively low urinary 3-methoxy-4-hydroxyphenyl glycol…

Indications (1)

Clinical Trials (4)

NCT00913822Phase 1Completed

To Demonstrate the Relative Bioavailability of Desipramine Hydrochloride Tablets

Started Dec 1987
NCT00913809Phase 1Completed

To Demonstrate the Relative Bioequivalency of Cord's 100 mg Desipramine HCL Tablets To Merrell Dow's 100 mg Norpramin Tablets

Started Dec 1987
NCT00913237Phase 1Completed

To Demonstrate the Relative Bioavailability of Desipramine Hydrochloride 50 mg Tablets

Started Jul 1987
NCT00914004Phase 1Completed

To Demonstrate the Relative Bioequivalency of Comparing Single 100 mg Doses Of Cord's 50 mg Desipramine HCL Tablets To Merrell Dow's 50 mg Norpramin Tablets