NDAORALCAPSULE, EXTENDED RELEASE
Approved
Jul 1982
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Mechanism of Action
Mechanisms of Action Norpace (disopyramide phosphate) is a Type 1 antiarrhythmic drug (i.e., similar to procainamide and quinidine). In animal studies Norpace decreases the rate of diastolic depolarization (phase 4) in cells with augmented automaticity, decreases the upstroke velocity (phase 0) and…