NDAORALCAPSULEPriority Review
Approved
Sep 1977
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Mechanism of Action
Mechanisms of Action Disopyramide phosphate is a Type 1 antiarrhythmic drug (i.e., similar to procainamide and quinidine). In animal studies, disopyramide phosphate decreases the rate of diastolic depolarization (phase 4) in cells with augmented automaticity, decreases the upstroke velocity (phase…