NIZORAL
LOE ApproachingNDATOPICALSHAMPOO
Approved
Aug 1990
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
1/8 — Limited
Drug data last refreshed 9h ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
NIZORAL is a topical antifungal shampoo containing ketoconazole, approved in 1990 for treating tinea pedis and other tinea infections. It works by inhibiting fungal cytochrome P450 enzymes, disrupting ergosterol synthesis and fungal cell membrane integrity. The product is a mature small-molecule dermatology asset in the Johnson & Johnson portfolio.
LOE Approaching
Product faces moderate competitive pressure (30/100) with approaching loss of exclusivity, signaling defensive commercial strategy and potential team contraction.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
NIZORAL offers limited career growth opportunity given its LOE-approaching status and zero linked job openings. Working on this asset suits professionals focused on mature brand management, defensive strategy, and operational efficiency rather than high-growth advancement.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.