NIZORAL ANTI-DANDRUFF

LOE ApproachingSM

ketoconazole

NDATOPICALSHAMPOO
Approved
Oct 1997
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

Cytochrome P450 3A4 Inhibitors

Pharmacologic Class:

Azole Antifungal

Clinical Trials (5)

NCT01969669Phase 1Completed

A Study to Assess the Effect of Ketoconazole on the Metabolism of ABT-199

Started Dec 2013
12 enrolled
Non-Hodgkin's Lymphoma
NCT01765556Phase 1Withdrawn

A Pharmacokinetics Study to Investigate the Effect of Ketoconazole on Vemurafenib in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma

Started Oct 2013
0
Malignant Melanoma, Neoplasms
NCT01925638Phase 1Completed

Effect of Ketoconazole on the Pharmacokinetics of Refametinib

Started Sep 2013
18 enrolled
Drug Interactions
NCT01924299Phase 1Completed

A Study of Baricitinib When Administered With Ketoconazole or Fluconazole in Healthy Participants

Started Aug 2013
36 enrolled
Healthy Volunteers
NCT01896323Phase 1Completed

CC-223 and Ketoconazole Drug-Drug Interaction Study

Started Jul 2013
14 enrolled
Healthy Volunteers