NDANASALSPRAY, METERED
Approved
Mar 1996
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Mechanism of Action
Pharmacologic Action Nicotine, the chief alkaloid in tobacco products, binds stereo-selectively to nicotinic-cholinergic receptors at the autonomic ganglia, in the adrenal medulla, at neuromuscular junctions, and in the brain. Two types of central nervous system effects are believed to be the basis…
Pharmacologic Class:
Cholinergic Nicotinic Agonist
Clinical Trials (5)
Phase 3 Trial Evaluating the Efficacy and Safety of Cytisinicline for Vaping Cessation in Adults Using Nicotine-Containing E Cigarettes
Started May 2026
800 enrolled
Vaping Cessation
Nicotine Influence on the Retina Following the Use of Electronic Cigarette
Started Aug 2022
44 enrolled
Electronic Cigarette UseRetina; Change
Comparative Effectiveness of Cystine Versus Nicotine Replacement Therapy
Started Jan 2022
1,307 enrolled
Nicotine Addiction
Effectiveness of Combination Varenicline and Oral Nicotine Replacement Therapy (COMBO)
Started Jan 2020
34 enrolled
Smoking Cessation
Daily Liraglutide for Nicotine Dependence
Started Nov 2018
40 enrolled
Smoking CessationWeight, Body