NDAINJECTIONINJECTABLEPriority Review
Approved
Mar 1955
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
3/8 — Basic
Priority Review
NESACAINE (chloroprocaine hydrochloride) by Fresenius Kabi is clinical pharmacology chloroprocaine, like other local anesthetics, blocks the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse and by reducing the rate of rise of the action potential. First approved in 1955.
Drug data last refreshed 9h ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
NESACAINE (chloroprocaine HCl) is a local anesthetic injectable that blocks nerve impulse generation and conduction for rapid-onset pain relief. It is indicated for transient neurological symptoms and works by increasing the electrical threshold in nerve fibers, slowing impulse propagation. Onset occurs within 6–12 minutes with duration up to 60 minutes depending on dose and route.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30%), signaling transition from growth-focused to defensive/retention teams.
Mechanism of Action
CLINICAL PHARMACOLOGY Chloroprocaine, like other local anesthetics, blocks the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse and by reducing the rate of rise of the…
Indications
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.