NDAINJECTIONINJECTABLEPriority Review
Approved
Mar 1955
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
3/8 — Basic
Priority Review
NESACAINE (chloroprocaine hydrochloride) by Fresenius Kabi is clinical pharmacology chloroprocaine, like other local anesthetics, blocks the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse and by reducing the rate of rise of the action potential. First approved in 1955.
Drug data last refreshed 23h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
NESACAINE (chloroprocaine hydrochloride) is a short-acting local anesthetic administered by injection that blocks nerve impulse generation and conduction for pain relief during surgical and dental procedures. It works by increasing the electrical excitation threshold in nerves and slowing action potential propagation. Patients undergoing procedures requiring rapid-onset, short-duration local anesthesia are the primary users.
LOE Approaching
As a 69-year-old product approaching loss of exclusivity with moderate competitive pressure, team size and growth investment are likely constrained.
Mechanism of Action
CLINICAL PHARMACOLOGY Chloroprocaine, like other local anesthetics, blocks the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse and by reducing the rate of rise of the…
Indications
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.