NATACYN
LOE Approachingnatamycin
NDAOPHTHALMICSUSPENSIONPriority Review
Approved
Oct 1978
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
Priority Review
NATACYN (natamycin) is clinical pharmacology: natamycin is a tetraene polyene antibiotic derived from streptomyces natalensis . First approved in 1978.
Drug data last refreshed 11h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
NATACYN (natamycin) is a tetraene polyene antibiotic ophthalmic suspension indicated for fungal eye infections. It works by binding to fungal cell membrane sterols, altering membrane permeability and depleting essential cellular constituents, making it predominantly fungicidal against yeasts and filamentous fungi including Candida and Aspergillus. Topical administration produces effective corneal concentrations with minimal systemic absorption.
$0.767MPart D
LOE ApproachingNiche ophthalmic specialty product with minimal Part D claims (1,506 in 2023) facing lifecycle decline and contracting commercial opportunity.
Mechanism of Action
CLINICAL PHARMACOLOGY: Natamycin is a tetraene polyene antibiotic derived from Streptomyces natalensis . It possesses in vitro activity against a variety of yeast and filamentous fungi, including Candida, Aspergillus, Cephalosporium, Fusarium and Penicillium . The mechanism of action appears to be…
Pharmacologic Class:
Polyene Antimicrobial
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.