NDANASALSPRAY, METERED
Approved
Jan 1997
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
NASALCROM (cromolyn sodium) by Blacksmith Medicines is clinical pharmacology: in vitro and in vivo animal studies have shown that cromolyn sodium inhibits the release of mediators from sensitized mast cells. First approved in 1997.
Drug data last refreshed 2h ago · AI intelligence enriched 6d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
NASALCROM is a metered nasal spray containing cromolyn sodium, a mast cell stabilizer approved in 1997 for allergic rhinitis. It works by inhibiting the release of histamine and leukotrienes from sensitized mast cells, with no intrinsic antihistamine or glucocorticoid activity. Patients use it as a preventive agent before allergen exposure.
LOE Approaching
As a mature, off-patent product approaching loss of exclusivity, the brand team is likely optimizing margins and managing formulary access rather than driving market expansion.
Mechanism of Action
CLINICAL PHARMACOLOGY: In vitro and in vivo animal studies have shown that cromolyn sodium inhibits the release of mediators from sensitized mast cells. Cromolyn sodium acts by inhibiting the release of histamine and leukotrienes (SRS-A) from the mast cell. Cromolyn sodium has no intrinsic…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on NASALCROM offers limited traditional pharma career progression, with linked roles skewing toward supply chain, IT, and operational functions rather than commercial or medical affairs. Career growth is constrained by the product's mature lifecycle and commoditized market position.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.