NDAORALTABLET
Approved
Mar 1960
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
1/8 — Limited
Drug data last refreshed 13h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
NAQUIVAL is a fixed-dose oral antihypertensive combination tablet containing reserpine (an alkaloid antihypertensive) and trichlormethiazide (a thiazide diuretic), approved in 1960. The combination targets hypertension through dual mechanisms: reserpine depletes catecholamine stores in sympathetic neurons, while trichlormethiazide promotes sodium and water excretion. This product represents a legacy antihypertensive regimen from the early era of combination therapy.
LOE Approaching
This product is in late-stage lifecycle with minimal linked job openings, suggesting a mature brand with minimal commercial expansion opportunities.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on NAQUIVAL offers minimal career growth potential given its approaching loss of exclusivity, legacy status, and zero linked job openings. Roles on this product are best suited to early-career professionals gaining experience in mature portfolio management or those seeking stable, lower-stakes assignments.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.