NDATOPICALCREAM
Approved
Jan 1979
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
8
Data completeness
3/8 — Basic
MYCELEX (clotrimazole) by Bayer is clinical pharmacology clotrimazole is a broad-spectrum antifungal agent that is used for the treatment of dermal infections caused by various species of pathogenic dermatophytes, yeasts, and malassezia furfur . First approved in 1979.
Drug data last refreshed 1h ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
MYCELEX (clotrimazole) is a broad-spectrum topical antifungal cream approved in 1979 for treatment of dermal fungal infections including vulvovaginal candidiasis, oral candidiasis, and various mycoses. It works by disrupting fungal cell membranes through inhibition of ergosterol synthesis, causing leakage of intracellular contents and cell death. The drug exhibits fungistatic and fungicidal activity against dermatophytes, yeasts, and Malassezia species with minimal systemic absorption.
LOE Approaching
Product approaching loss of exclusivity with modest competitive pressure (30/100); brand team focus shifts to lifecycle extension and transition planning.
Mechanism of Action
CLINICAL PHARMACOLOGY Clotrimazole is a broad-spectrum antifungal agent that is used for the treatment of dermal infections caused by various species of pathogenic dermatophytes, yeasts, and Malassezia furfur . The primary action of clotrimzole is against dividing and growing organisms. In vitro ,…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.