NDAINTRATHECALINJECTABLE
Approved
Feb 1982
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
MPI INDIUM DTPA IN 111 (indium in-111 pentetate disodium) by GE HealthCare is radiopharmaceutical activity [moa]. Approved for radioactive diagnostic agent [epc]. First approved in 1982.
Drug data last refreshed 10h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
MPI Indium DTPA IN-111 is a radiopharmaceutical diagnostic agent containing indium-111 pentetate disodium, administered intrathecally for nuclear medicine imaging. It localizes in the central nervous system to detect cerebrospinal fluid flow abnormalities and diagnose conditions like normal pressure hydrocephalus and CSF leakage. The compound works via radioactive decay, emitting gamma radiation that is detected by gamma cameras.
LOE Approaching
As a mature diagnostic product approaching loss of exclusivity, the brand team is likely focused on market defense and operational efficiency rather than expansion.
Mechanism of Action
Radiopharmaceutical Activity
Pharmacologic Class:
Radioactive Diagnostic Agent
Indications (1)
Career Relevance
Working on MPI Indium DTPA IN-111 offers exposure to specialized diagnostic imaging markets, regulatory compliance in radiopharmaceuticals, and healthcare provider relationships in nuclear medicine departments. However, the LOE-approaching lifecycle and zero linked job openings indicate limited expansion opportunities; roles are primarily focused on market defense, compliance, and operational efficiency.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.