MOXIDECTIN
LOE Approachingmoxidectin
NDAORALTABLETPriority Review
Approved
Jun 2018
Lifecycle
LOE Approaching
Competitive Pressure
25/100
Clinical Trials
4
Data completeness
3/8 — Basic
Priority Review
MOXIDECTIN (moxidectin) is moxidectin, a macrocyclic lactone, is an anthelmintic drug [see microbiology ( )] . First approved in 2018.
Drug data last refreshed 8h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Moxidectin is an oral tablet anthelmintic agent belonging to the macrocyclic lactone class of drugs. It is indicated for parasitic infections treatable by anthelmintic mechanisms. The drug works by disrupting neuromuscular function in parasitic organisms, leading to paralysis and elimination.
LOE Approaching1.3 years to LOE
Product approaching loss of exclusivity with moderate competitive pressure (25% intensity); brand team may be transitioning to generic optimization or lifecycle extension strategies.
Mechanism of Action
Moxidectin, a macrocyclic lactone, is an anthelmintic drug [see Microbiology ( )] .
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (4)
Pediatric Pharmacokinetics And Safety Study Of Moxidectin
Started Apr 2011
0Onchocerciasis
Study Evaluating The Co-Administration Of Moxidectin And Midazolam In Healthy Subjects
Started Apr 2009
38 enrolled
Healthy
Study Evaluating The Effect Of High-Fat Meal On Bioavailability And Pharmacokinetics Of Single Dose Of Moxidectin
Started Nov 2008
54 enrolled
Infection
Study Evaluating The Excretion Of Moxidectin Into The Breast Milk Of Lactating, Non-Breastfeeding Women
Started Nov 2008
12 enrolled
Infection
Why This Matters for Your Career
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.