MOTEGRITY

Peak

prucalopride

NDAORALTABLET
Approved
Dec 2018
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
15

Mechanism of Action

Prucalopride, a selective serotonin type 4 (5-HT 4 ) receptor agonist, is a gastrointestinal (GI) prokinetic agent that stimulates colonic peristalsis (high-amplitude propagating contractions [HAPCs]), which increases bowel motility. Prucalopride was devoid of effects mediated via 5-HT 2A , 5-HT 2B…

Clinical Trials (5)

NCT04838522N/ARecruiting

A Study of Prucalopride in Breastfeeding Women With Constipation

Started Mar 2022
12 enrolled
Chronic Idiopathic Constipation (CIC)
NCT04961840N/AActive Not Recruiting

A Study to Assess Maternal and Fetal Outcomes After Taking Prucalopride During Pregnancy

Started Jan 2022
100 enrolled
ConstipationPregnancy
NCT04759833Phase 3Terminated

A Study of Prucalopride For Functional Constipation in Children and Teenagers

Started Jul 2021
175 enrolled
Constipation
NCT04869280N/AActive Not Recruiting

Post-Marketing Study of Prucalopride Safety In Pregnancy

Started May 2021
127 enrolled
Chronic Idiopathic Constipation (CIC)
NCT02228616Phase 4Completed

Efficacy and Safety of Prucalopride in Combination With Polyethylene Glycol or Lactulose in Women With Chronic Constipation

Started Oct 2014
280 enrolled
Constipation