NDAORALCONCENTRATE
Approved
Dec 1979
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
MOBAN (molindone hydrochloride) by Molecular Devices is clinical pharmacology molindone hydrochloride has a pharmacological profile in laboratory animals which predominantly resembles that of other antipsychotic agents causing reduction of spontaneous locomotion and aggressiveness, suppression of a conditioned response and antagonism of the bizarre stereotyped behavior and hyperactivity induced by amphetamines. Approved for schizophrenia. First approved in 1979.
Drug data last refreshed 7h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
MOBAN (molindone hydrochloride) is an oral antipsychotic concentrate approved in 1979 for schizophrenia treatment. It works by reducing spontaneous locomotion and aggressiveness while suppressing bizarre behavior, exerting effects on the ascending reticular activating system with a pharmacological effect lasting 24-36 hours per dose. The drug is rapidly absorbed and metabolized with 36 recognized metabolites and minimal urinary/fecal excretion of unmetabolized drug.
LOE Approaching
As a legacy antipsychotic approaching loss of exclusivity with minimal current market presence, career opportunities are limited to specialty maintenance roles rather than growth-oriented positions.
Mechanism of Action
CLINICAL PHARMACOLOGY Molindone Hydrochloride has a pharmacological profile in laboratory animals which predominantly resembles that of other antipsychotic agents causing reduction of spontaneous locomotion and aggressiveness, suppression of a conditioned response and antagonism of the bizarre…
Indications (1)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.