NDAORALTABLET
Approved
Jan 1974
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
MOBAN (molindone hydrochloride) by Molecular Devices is clinical pharmacology molindone hydrochloride has a pharmacological profile in laboratory animals which predominantly resembles that of other antipsychotic agents causing reduction of spontaneous locomotion and aggressiveness, suppression of a conditioned response and antagonism of the bizarre stereotyped behavior and hyperactivity induced by amphetamines. Approved for schizophrenia. First approved in 1974.
Drug data last refreshed 6d ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
MOBAN (molindone hydrochloride) is an oral antipsychotic tablet approved in 1974 for the treatment of schizophrenia. It works by reducing spontaneous locomotion and aggressiveness, suppressing conditioned responses, and antagonizing amphetamine-induced bizarre behavior through effects on the ascending reticular activating system. The drug is rapidly absorbed and metabolized orally, with a 24-36 hour duration of action from a single dose.
LOE Approaching
Late-stage legacy product with minimal commercial growth trajectory; expect declining headcount and maintenance-focused portfolio positioning.
Mechanism of Action
CLINICAL PHARMACOLOGY Molindone Hydrochloride has a pharmacological profile in laboratory animals which predominantly resembles that of other antipsychotic agents causing reduction of spontaneous locomotion and aggressiveness, suppression of a conditioned response and antagonism of the bizarre…
Indications (1)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.