MIRAPEX by Boehringer Ingelheim is clinical pharmacology mechanism of action pramipexole is a nonergot dopamine agonist with high relative in vitro specificity and full intrinsic activity at the d 2 subfamily of dopamine receptors, binding with higher affinity to d 3 than to d 2 or d 4 receptor subtypes. Approved for the signs, symptoms of idiopathic parkinson's disease, moderate-to-severe primary restless legs syndrome (rls). First approved in 1997.
Drug data last refreshed 6d ago
CLINICAL PHARMACOLOGY Mechanism of Action Pramipexole is a nonergot dopamine agonist with high relative in vitro specificity and full intrinsic activity at the D 2 subfamily of dopamine receptors, binding with higher affinity to D 3 than to D 2 or D 4 receptor subtypes. Parkinson’s Disease: The…
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Safety and Efficacy of Long-term Daily Use of Mirapex®-LA Tablets in Patients With Parkinson's Disease
Kinetic Tremor in Parkinsons Disease: Its Course Under Pramipexole (Mirapexin®) Treatment and Impact on Quality of Life
Safety and Effect of Mirapex(Pramipexole) Tablet Among Korean RLS
A 6 Week Trial to Study the Efficacy and Safety of a Starting Dose 0.25 mg Pramipexole (Mirapex) in Patients With RLS
Study of (Mirapex) Pramipexole for the Early Treatment of Parkinsons Disease (PD)