NDAOPHTHALMICFOR SOLUTION
Approved
Sep 1993
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
MIOCHOL-E (acetylcholine chloride) by Bausch + Lomb is clinical pharmacology acetylcholine is a naturally occurring neurohormone which mediates nerve impulse transmission at all cholinergic sites involving somatic and autonomic nerves. First approved in 1993.
Drug data last refreshed 55m ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
MIOCHOL-E is an intraocular solution of acetylcholine chloride, a naturally occurring neurotransmitter that causes rapid miosis (pupil constriction) when applied directly to the iris during ocular surgery. It works by mimicking acetylcholine's action at cholinergic receptors, enabling precise pupil control during anterior segment procedures. The drug has limited systemic penetration due to rapid enzymatic degradation.
LOE Approaching
Mature niche ophthalmic product with limited commercial expansion; small, stable brand team focused on maintenance.
Mechanism of Action
CLINICAL PHARMACOLOGY Acetylcholine is a naturally occurring neurohormone which mediates nerve impulse transmission at all cholinergic sites involving somatic and autonomic nerves. After release from the nerve ending, acetylcholine is rapidly inactivated by the enzyme acetylcholinesterase by…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
MIOCHOL-E offers limited career growth given its mature, niche market position and approaching loss of exclusivity. Roles are primarily maintenance-focused, suited to professionals seeking stability in specialized ophthalmic surgical markets rather than high-visibility brand launches.
Medical Science Liaison (MSL)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.