MIOCHOL
LOE ApproachingNDAOPHTHALMICFOR SOLUTION
Approved
Oct 1973
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
MIOCHOL by Novartis is clinical pharmacology acetylcholine is a naturally occurring neurohormone which mediates nerve impulse transmission at all cholinergic sites involving somatic and autonomic nerves. First approved in 1973.
Drug data last refreshed 15h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
MIOCHOL is an intraocular solution of acetylcholine, a naturally occurring cholinergic neurotransmitter that directly acts on the iris to produce rapid miosis (pupil constriction). Administered topically during ophthalmic surgery, it mediates nerve impulse transmission at cholinergic sites and is rapidly inactivated by acetylcholinesterase. It is used intraoperatively in ophthalmic procedures where pupil constriction is therapeutically desired.
LOE Approaching
Approaching loss of exclusivity with moderate competitive pressure; limited growth opportunities indicate smaller brand teams focused on retention and market defense.
Mechanism of Action
CLINICAL PHARMACOLOGY Acetylcholine is a naturally occurring neurohormone which mediates nerve impulse transmission at all cholinergic sites involving somatic and autonomic nerves. After release from the nerve ending, acetylcholine is rapidly inactivated by the enzyme acetylcholinesterase by…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
MIOCHOL roles are limited in number and concentrated in mature commercial and medical affairs functions. This is a legacy surgical product with declining career momentum, suitable for professionals seeking stable but not growth-oriented positions in pharmaceutical operations.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.