MINOCIN
LOE ApproachingNDAORALCAPSULE
Approved
May 1990
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
MINOCIN by Bausch + Lomb is clinical pharmacology following a single dose of minocin 200 mg administered intravenously to 10 healthy male subjects, serum concentrations of minocycline ranged from 2. Approved for infections caused by the following gram-negative bacteria, infections caused by the following gram-positive bacteria, the treatment of the following infections due to susceptible isolates of the designated bacteria: rocky mountain spotted fever and 5 more indications. First approved in 1990.
Drug data last refreshed 23h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
MINOCIN (minocycline) is an oral tetracycline antibiotic approved in 1990 that works by inhibiting bacterial protein synthesis to treat a broad spectrum of gram-positive and gram-negative infections, including rickettsial diseases like Rocky Mountain spotted fever and Q fever. It demonstrates bacteriostatic activity against over 30 bacterial species and other microorganisms including Chlamydia, Mycoplasma, and Treponema species.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30%) signals transition planning and potential organizational restructuring or consolidation within the brand team.
Mechanism of Action
CLINICAL PHARMACOLOGY Following a single dose of Minocin 200 mg administered intravenously to 10 healthy male subjects, serum concentrations of minocycline ranged from 2.52 to 6.63 mcg/mL (average 4.18 mcg/mL) at the end of infusion and 0.82 to 2.64 mcg/mL (average 1.38 mcg/mL) after 12 hours. In a…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.