NDAINJECTIONINJECTABLE
Approved
Oct 1972
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
1
Data completeness
4/8 — Partial
MINOCIN (minocycline hydrochloride) by Pfizer is clinical pharmacology following a single dose of minocin 200 mg administered intravenously to 10 healthy male subjects, serum concentrations of minocycline ranged from 2. First approved in 1972.
Drug data last refreshed 19h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
MINOCIN (minocycline hydrochloride) is a tetracycline-class antibiotic administered intravenously that works by inhibiting bacterial protein synthesis to provide bacteriostatic activity. It treats a broad spectrum of Gram-positive and Gram-negative bacterial infections, as well as atypical organisms including Chlamydia, Mycoplasma, and Rickettsia. The IV formulation allows for systemic delivery in hospitalized or seriously ill patients who cannot tolerate oral therapy.
Peak6.1 years to LOE
MINOCIN operates in a mature, established antibiotic market with stable demand; commercial teams are likely small and focused on maintenance rather than growth initiatives.
Mechanism of Action
CLINICAL PHARMACOLOGY Following a single dose of Minocin 200 mg administered intravenously to 10 healthy male subjects, serum concentrations of minocycline ranged from 2.52 to 6.63 mcg/mL (average 4.18 mcg/mL) at the end of infusion and 0.82 to 2.64 mcg/mL (average 1.38 mcg/mL) after 12 hours. In a…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.