METRONIDAZOLE
LOE ApproachingNDAORALTABLET
Approved
Mar 1982
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
4/8 — Partial
METRONIDAZOLE by Fosun Pharma is clinical pharmacology absorption disposition of metronidazole in the body is similar for both oral and intravenous dosage forms. Approved for the treatment of asymptomatic t, the treatment of acute intestinal amebiasis (amebic dysentery), amebic liver abscess and 1 more indications. First approved in 1982.
Drug data last refreshed 7h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Metronidazole is a small-molecule nitroimidazole antibiotic with bactericidal and trichomonacidal activity used to treat anaerobic bacterial infections, parasitic infections (trichomoniasis, amebiasis), and amebic liver abscess. The drug works by disrupting DNA synthesis in susceptible organisms and exhibits excellent tissue penetration, including into cerebrospinal fluid and hepatic abscess pus.
LOE Approaching
Product is in LOE-approaching phase with moderate competitive pressure (30%), signaling declining market opportunity and likely downsizing or consolidation of the brand team.
Mechanism of Action
CLINICAL PHARMACOLOGY Absorption Disposition of metronidazole in the body is similar for both oral and intravenous dosage forms. FLAGYL 375 capsules have been shown to have a rate and extent of absorption similar to metronidazole tablets (FLAGYL) and were bioequivalent at an equal single dose of…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.