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METOCLOPRAMIDE HYDROCHLORIDE (metoclopramide hydrochloride) by Merck & Co. is clinical pharmacology metoclopramide stimulates motility of the upper gastrointestinal tract without stimulating gastric, biliary, or pancreatic secretions. Approved for vomiting associated with emetogenic cancer chemotherapy, postoperative nausea, vomiting in those circumstances where nasogastric suction is undesirable. First approved in 1987.
CLINICAL PHARMACOLOGY Metoclopramide stimulates motility of the upper gastrointestinal tract without stimulating gastric, biliary, or pancreatic secretions. Its mode of action is unclear. It seems to sensitize tissues to the action of acetylcholine. The effect of metoclopramide on motility is not…
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Merck & Co. is hiring 10 roles related to this product