METHOTREXATE SODIUM
LOE Approachingcalcium chloride; dextrose; glutathione disulfide; magnesium chloride; potassium chloride; sodium bicarbonate; sodium chloride; sodium phosphate
NDAIRRIGATIONSOLUTION
Approved
Nov 1991
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
1/8 — Limited
Drug data last refreshed 11h ago · AI intelligence enriched 4d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Methotrexate Sodium is an irrigation solution containing methotrexate in a balanced electrolyte formulation (calcium chloride, dextrose, glutathione disulfide, magnesium chloride, potassium chloride, sodium bicarbonate, sodium chloride, sodium phosphate). The specific clinical indication is not documented in available data, but the irrigation route suggests use in surgical or topical applications. This formulation is designed to maintain cellular viability during procedures requiring extended irrigation.
LOE Approaching
With LOE approaching and 30% competitive pressure, this product is in a defensive positioning phase with likely downsizing of commercial support.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
This product currently shows zero linked job openings, reflecting its mature lifecycle stage and approaching loss of exclusivity. Career opportunities on this brand are limited and likely focused on legacy product support and transition planning rather than growth initiatives.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.