METHOTREXATE SODIUM
LOE Approachingcalcium chloride; dextrose; glutathione disulfide; magnesium chloride; potassium chloride; sodium bicarbonate; sodium chloride; sodium phosphate
NDAIRRIGATIONSOLUTION
Approved
Nov 1991
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
1/8 — Limited
Drug data last refreshed 4h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Methotrexate Sodium is a chemotherapy and immunosuppressant agent formulated as an irrigation solution containing methotrexate with electrolytes and supportive components. The product is indicated for intracavitary or regional administration in various malignancies and autoimmune conditions. This is a legacy NDA-approved product from Bristol Myers Squibb with approval dating to 1991.
LOE Approaching
Product is approaching loss of exclusivity with moderate competitive pressure (30%), signaling potential contraction of brand team size and shift toward generic mitigation strategies.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Zero linked job openings indicate this product is not actively hiring; career opportunities are extremely limited and primarily focused on defensive commercial strategies. Working on this product offers stability in a mature market but limited advancement potential compared to growth-stage products.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.