METHOTREXATE SODIUM
LOE Approachingcalcium chloride; dextrose; glutathione disulfide; magnesium chloride; potassium chloride; sodium bicarbonate; sodium chloride; sodium phosphate
NDAIRRIGATIONSOLUTION
Approved
Nov 1991
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
1/8 — Limited
Drug data last refreshed 6d ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Methotrexate Sodium is a chemotherapy and immunosuppressive agent delivered as an irrigation solution containing balanced electrolytes and antioxidants. The product is used for irrigation purposes in clinical settings, likely supporting methotrexate administration or post-treatment care. The electrolyte and glutathione components suggest a formulation designed to protect tissue during or after methotrexate exposure.
LOE Approaching
Product is approaching loss of exclusivity with moderate competitive pressure (30%), signaling potential team consolidation and shift toward defensive positioning.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on this product offers limited growth opportunity given its LOE-approaching lifecycle and zero linked job postings. Career progression would focus on defensive commercial strategies, cost optimization, and potential transition to next-generation therapies within Bristol Myers Squibb's oncology portfolio.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.