METHOTREXATE

Peak

methotrexate

NDAINTRAVENOUSSOLUTION
Approved
Aug 2020
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
20

Clinical Trials (5)

NCT06590090Phase 2Not Yet Recruiting

Natrunix in Combination With Methotrexate for Rheumatoid Arthritis Treatment

Started Jul 2026
108 enrolled
Rheumatoid Arthritis
NCT07446400Phase 1Not Yet Recruiting

A Trial to Examine the Interaction of Repinatrabit With Ethinyl Estradiol/Norethindrone, Metformin,Carbamazepine, Rosuvastatin, and Methotrexate When Administered Together

Started Mar 2026
48 enrolled
Healthy Volunteers
NCT07388498Phase 3Recruiting

A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout

Started Feb 2026
270 enrolled
Uncontrolled Gout
NCT06895473Phase 2Recruiting

Intrathecal Cytarabine, Methotrexate, and Hydrocortisone for the Prevention of High-Grade Chimeric Antigen Receptor T-Cell-Associated Neurotoxicity Syndrome

Started Jun 2025
26 enrolled
Hematopoietic and Lymphatic System Neoplasm
NCT06615050Phase 3Recruiting

A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

Started Apr 2025
572 enrolled
Graft-versus-host Disease (GVHD)