ANDAORALTABLET
Approved
Mar 2020
Lifecycle
Post-LOE
Competitive Pressure
30/100
Clinical Trials
20
Mechanism of Action
mu-agonist; a synthetic opioid with multiple actions qualitatively similar to those of morphine, the most prominent of which involves the central nervous system and organs composed of smooth muscle. The principal therapeutic uses for methadone are for analgesia and for detoxification or maintenance…
Indications (3)
Clinical Trials (5)
Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Buprenorphine/Naloxone or Methadone
Started Dec 2025
Real-life Observational Study of Cancer Pain Management With Methadone
Started Feb 2022
136 enrolled
Cancer Pain
Islatravir and Methadone Pharmacokinetics (MK-8591-029)
Started Oct 2020
14 enrolled
HIV-1 Infection
Integrating Treatment for Mental Disorders in Methadone Clinics in Ukraine
Started Jul 2018
1,350 enrolled
DepressionOpioid Use Disorder
A Study to Assess the Drug-drug Interaction of BMS 663068 With Methadone and Also With Buprenorphine/Naloxone
Started Jan 2016
32 enrolled
Infection, Human Immunodeficiency Virus