NDAORALTABLET1 Generic Approved
Approved
Apr 1955
Lifecycle
LOE Approaching
Competitive Pressure
45/100
Clinical Trials
1
Data completeness
3/8 — Basic
Drug data last refreshed 3h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
MESTINON (pyridostigmine bromide) is an oral acetylcholinesterase inhibitor approved in 1955 for myasthenia gravis and related neuromuscular disorders. It works by blocking acetylcholinesterase enzyme, prolonging acetylcholine activity at the neuromuscular junction to improve muscle strength and function. The drug is a foundational treatment in neuromuscular disease management.
$0.007BPart D
LOE ApproachingProduct approaching loss of exclusivity with modest Medicare spending ($7M in 2023), signaling potential team downsizing and shift toward generic support or adjacent indications.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Testing Mestinon and Exercise in Fibromyalgia
Started Sep 2002
178 enrolled
Fibromyalgia
Career Relevance
Working on MESTINON offers stability in a niche, established market but limited growth opportunity due to LOE approach and minimal clinical pipeline. Career value lies in legacy brand management, generic transition strategy, and maintaining market share in a specialized neuromuscular indication.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.