NDAORALTABLET
Approved
Jun 1998
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
58
Data completeness
4/8 — Partial
Drug data last refreshed 9h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
MAXALT (rizatriptan benzoate) is an oral triptan approved in 1998 for acute treatment of migraine attacks and cluster headaches. It works by binding to 5-HT1B/1D serotonin receptors on intracranial blood vessels and trigeminal sensory nerves, causing cranial vasoconstriction and inhibiting neuropeptide release. The mechanism provides rapid symptom relief during migraine episodes.
$1MPart D
LOE ApproachingDeclining
Approaching loss of exclusivity with minimal Part D spending signals a mature, consolidating market with contracting team investment opportunities.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (58)
Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)
Started Mar 2026
450 enrolled
Von Hippel-Lindau DiseaseCarcinoma, Renal Cell
A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)
Started Nov 2025
904 enrolled
Renal Cell Carcinoma
Ceftolozane/Tazobactam Versus Meropenem for Febrile Neutropenia on Patients Colonized With or at Risk for Infection With Extended Spectrum Beta Lactamase - Producing Pathogens
Started Mar 2025
176 enrolled
Febrile Neutropenia
Supporting the National Expansion of HPV-based Cervical Cancer Screening in Tanzania Among Women Living with HIV
Started May 2024
2,000 enrolled
Cervical Cancer
Preterm Immune System Development and Response to Immunization
Started Dec 2022
145 enrolled
Immune System DisorderPretermVaccination Failure
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.