MARCAINE HYDROCHLORIDE PRESERVATIVE FREE
LOE Approachingbupivacaine hydrochloride and epinephrine
NDAINJECTIONINJECTABLEPriority Review
Approved
Oct 1972
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Mechanism of Action
impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse, and by reducing the rate of rise of the action potential. In general, the progression of anesthesia is related to the diameter, myelination, and conduction…