MARCAINE

LOE Approaching

bupivacaine hydrochloride in dextrose

NDASPINALINJECTABLE
Approved
May 1984
Lifecycle
LOE Approaching
Competitive Pressure
30/100

Mechanism of Action

impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse, and by reducing the rate of rise of the action potential. In general, the progression of anesthesia is related to the diameter, myelination, and conduction…