NDAORALTABLETPriority Review
Approved
Jul 2000
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
4/8 — Partial
Priority Review
MALARONE (atovaquone and proguanil hydrochloride) by GSK. Approved for antimalarial [epc]. First approved in 2000.
Drug data last refreshed 11h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Malarone is an oral antimalarial combination tablet containing atovaquone and proguanil hydrochloride, approved by the FDA in 2000. It is indicated for the treatment and prevention of malaria caused by Plasmodium falciparum. The dual mechanism targets the malaria parasite through complementary pathways, making it effective for both treatment and chemoprophylaxis in travelers.
$0.003BPart D
LOE ApproachingDeclining
Nearing loss of exclusivity with minimal Medicare spending signals a small, declining brand team focused on transition planning and generic preparation.
Mechanism of Action
Pharmacologic Class:
Antimalarial
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on Malarone offers limited career growth potential given its LOE-approaching status and minimal linked job openings. Roles are likely defensive, focused on market maintenance, margin protection, and transition planning rather than growth, making this primarily a stabilization assignment rather than a career-advancing opportunity.
Brand ManagerProduct Manager
Worked on MALARONE at GSK? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.