LUTATHERA

Peak

lutetium lu 177 dotatate

NDAINTRAVENOUSSOLUTIONPriority Review
Approved
Jan 2018
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
5

Mechanism of Action

177 dotatate binds to somatostatin receptors with highest affinity for subtype 2 somatostatin receptors (SSTR2). Upon binding to somatostatin receptor expressing cells, including malignant somatostatin receptor-positive tumors, the compound is internalized. The beta-minus emission from lutetium-177…

Clinical Trials (5)

NCT05247905Phase 2Active Not Recruiting

Comparing Capecitabine and Temozolomide in Combination to Lutetium Lu 177 Dotatate in Patients With Advanced Pancreatic Neuroendocrine Tumors

Started Feb 2023
31 enrolled
Metastatic Pancreatic Neuroendocrine TumorUnresectable Pancreatic Neuroendocrine Carcinoma
NCT04946305N/ACompleted

A Post Marketing Surveillance on Lutathera® in Patients With Somatostatin Receptor Positive Gastroenteropancreatic Neuroendocrine Tumor in Korea

Started May 2022
89 enrolled
Somatostatin Receptor-positive GEP-NET
NCT05844332N/ACompleted

LUTATHERA Injection General Use Result Survey

Started Dec 2021
347 enrolled
Somatostatin Receptor-positive Neuroendocrine Tumor
NCT04543955Phase 2Terminated

Telotristat With Lutathera in Neuroendocrine Tumors

Started Sep 2021
1 enrolled
Neuroendocrine Tumors
NCT05816720N/ACompleted

Retrospective Analysis of Patients Re-treated With Lutetium-177 DOTATATE (Lutathera®)

Started Sep 2021
31 enrolled
Neuroendocrine Tumor

Loss of Exclusivity

LOE Date
Jan 25, 2039
156 months away
Patent Expiry
Jan 25, 2039
Exclusivity Expiry
Oct 23, 2031

Patent Records (5)

Patent #ExpiryTypeUse Code
10596278
Jul 25, 2038
Product
12161732
Jul 25, 2038
Product
U-4036
12144873
Jul 25, 2038
U-4036
12168063
Jul 25, 2038
Product
U-4036
11904027
Jul 25, 2038
Product