LOVASTATIN

Post-LOESM

lovastatin

Merck & Co.

ANDAORALTABLET

Approved

Nov 2007

Lifecycle

Post-LOE

Competitive Pressure

30/100

Clinical Trials

Data completeness

5/8 — Partial

LOVASTATIN (lovastatin) by Merck & Co. is hydroxymethylglutaryl-coa reductase inhibitors [moa]. Approved for hmg-coa reductase inhibitor [epc]. First approved in 2007.

Drug data last refreshed 18h ago

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Mechanism of Action

Hydroxymethylglutaryl-CoA Reductase Inhibitors

Pharmacologic Class:

HMG-CoA Reductase Inhibitor

Indications

Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.

Clinical Trials (6)

NCT02603770Phase 1Completed

Compare Pharmacokinetic(PK) Profiles of XZK vs Lovastatin in Healthy Male Volunteers

Started Nov 2015

20 enrolled

Lipid Metabolism Disorder

NCT00963664Phase 2Withdrawn

Evaluation of Interferon-Lovastatin Therapy for Malignant Melanoma

Started Dec 2009

250 enrolled

MelanomaMalignant Melanoma

NCT00352599Phase 1Completed

Trial to Evaluate the Safety of Lovastatin in Individuals With Neurofibromatosis Type I (NF1)

Started Sep 2009

44 enrolled

Neurofibromatosis 1

NCT00853580Phase 2Completed

A Randomized Placebo-Controlled Study of Lovastatin in Children With Neurofibromatosis Type 1

Started Jul 2009

146 enrolled

Neurofibromatosis Type 1

NCT00302952Phase 2Terminated

Lovastatin for the Treatment of Mildly Active Rheumatoid Arthritis

Started Nov 2007

64 enrolled

Rheumatoid Arthritis

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Data Sources

Drug label: DailyMed / FDA
Clinical trials: ClinicalTrials.gov
Patent data: FDA Orange Book
Spending data: CMS Medicare

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.