LOTENSIN HCT

LOE Approaching

benazepril hydrochloride and hydrochlorothiazide

NDAORALTABLET
Approved
May 1992
Lifecycle
LOE Approaching
Competitive Pressure
30/100

Mechanism of Action

CLINICAL PHARMACOLOGY Mechanism of Action Benazepril and benazeprilat inhibit angiotensin converting enzyme (ACE) in human subjects and in animals. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. Angiotensin II also…

Pharmacologic Class:

Thiazide Diuretic

Indications (1)