LOTENSIN

LOE Approaching

benazepril hydrochloride

NDAORALTABLET
Approved
Jun 1991
Lifecycle
LOE Approaching
Competitive Pressure
30/100

Mechanism of Action

angiotensin-converting enzyme (ACE) in human subjects and animals. Benazeprilat has much greater ACE inhibitory activity than does benazepril. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. Angiotensin II also…